Zoloft

Zoloft, the brand name for the drug Sertraline, is part of the group of antidepressant drugs known as selective serotonin reuptake inhibitors, or SSRIs. These drugs are often used in the treatment of major depression and can help manage the symptoms of anxiety disorders as well.

Function of Zoloft


Selective serotonin reuptake inhibitors work by inhibiting the removal of the neurotransmitter serotonin after it has been released into the synaptic channel. The serotonin remains active in the brain for longer, resulting in elevated mood and easing anxiety symptoms.

Drug Interactions and Side Effects of Zoloft


SSRIs like Zoloft can have dangerous interactions with the class of antidepressant drugs known as MAO inhibitors. If you are switching to an MAOI from Zoloft or vice versa, be sure you have discontinued one for at least two weeks before starting on the other. You should also not combine Zoloft with the drug Orap/pimozide. Some side effects related to taking Zoloft can include but are not limited to dry mouth, abdominal pain, loose stools, decreased sex drive and ejaculation difficulty, sweating and indigestion.

How to Take Zoloft


Zoloft is generally taken at 50 milligrams once a day. It is usually taken as a capsule or an oral concentrate. If you are using the oral concentrate, you will measure the proper amount with an eyedropper and add it to four ounces of either water, ginger ale, lemonade or lemon-lime soda or orange juice and drink immediately. Zoloft does not take immediate effect. You may have to build up levels in your blood stream for several weeks before you feel the effects of Zoloft. Even if you miss a dose of Zoloft, you should never double dose. If you decide to discontinue Zoloft, you must taper off slowly, so seek your doctor’s supervision while discontinuing use.

About Zoloft and other SSRIs for Depression


While Zoloft and other SSRIs have proven effective for the symptoms of depression for many people, it should be used in accompaniment with other treatment, such as psychoanalysis, cognitive behavioral techniques or some other form of psychotherapy. Some users, especially teens and children, may be at greater risk for suicidal or self-destructive behaviors as the drug starts to take effect so they need experienced counselors to monitor their progress. Many disorders have multiple causes, including biochemical imbalances in the brain but also environmental and psychosocial factors that need to be addressed with therapy. A multi-pronged approach to treatment tends to have better long-term results than drug therapy by itself.
 

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