Function of Cymbalta
Cymbalta is an SNRI, or Selective Serotonin and Norepinephrine Reuptake Inhibitor. Like the SSRI anti-depressant drugs, Cymbalta blocks the reuptake of the neurotransmitter serotonin in the brain, allowing it to spend more time in the synaptic channel and elevate mood, but Cymbalta blocks the reuptake of another neurotransmitter, norepinephrine, as well, which may significantly boost the mood-elevating effect.
Drug Interactions and Side Effects with Cymbalta
Patients should never take Cymbalta if they have been taking any drug in the MAOIs, or monoamine oxidase inhibitor, family. The interaction effect between these two types of drugs can be fatal in some instances. The same is true of taking Cymbalta and thiroridzine. Cymbalta is also contraindicated for people with uncontrolled narrow-angle glaucoma. People with liver or kidney damage should not take Cymbalta. Side effects for Cymbalta may include constipation, nausea, sexual difficulties, urinary difficulties and changes in appetite.
How to Take Cymbalta
Cymbalta must be taken at the same time every day. If you miss a dose, you should take it as soon as you remember, but not if it is close to the next dose. You should not take two doses of Cymbalta close together. The capsule should be swallowed whole, not chewed or broken. Cymbalta is a slow-acting drug and it will take time for levels of the medication to build up in your bloodstream. This means that you will probably not experience any effects for several weeks. Even when you start to feel better, it is important to continue the medication as directed to maintain therapeutic levels in your bloodstream. Consult your doctor before you stop taking Cymbalta so you can develop a plan for weening yourself off the drug. Abrupt cessation may have adverse effects.
About Major Depression
Major depression is a very serious illness that can lead to isolation, inactivity and even suicide. While medication is important for those suffering from major depression, it is not a substitute for other kinds of therapy and support from friends and loved ones. When an anti-depressant medication starts to take effect, suicidal ideation and actions may temporarily increase, so it is very important to watch the patient and make sure they are receiving adequate therapy during this time.
