Cylert

Cylert is the brand name for pemoline, a central nervous system stimulant. Cylert has been found to cause severe liver damage and is no longer commercially available in most countries including the United States and Canada.

Function of Cylert


Cylert was formerlly used as a central nervous system (CNS) stimulant to treat attention deficit hyperactivity disorder (ADHD) in children. Its function was to increase attention and decrease restlessness. Although using a stimulant to decrease restlessness seems counter-intuitive, CNS stimulants have been known to have this effect in children. This phenomenon is generally referred to as the paradoxical effect.

Drug Interactions and Side Effects with Cylert


Studies have confirmed that Cylert causes serious liver damage and that its risks far outweigh its benefits. As a result, the drug has been taken off the market. If you find yourself in a country where Cylert is legal, you will probably be asked to sign a statement indicating you understand the risks of taking the drug. This is not recommended. There are many approved drugs that can be used to treat ADHD that are much safer than Cylert. When Cylert was prescribed, it was contraindicated with MAO inhibitors, amphetamines, asthma medications, anti-convulsants and a variety of other medications.

How to Take Cylert


Cylert is not an approved drug and should not be taken at all. When it was prescribed, it was generally as a chewable tablet which needed to be fully chewed before swallowing. The typically prescribed dosage was 37.5 milligrams each morning, an amount that could be increased at the doctor's discretion. Cylert was habit-forming if taken at too high a dose and for too long, so the course of treatment with Cylert needed to be carefully monitored even when its effects on the liver were not fully analyzed.

CMS Stimulants, Cylert and ADHD

There are a number of approved CNS stimulants on the market that are used for the treatment of ADHD in children. Although many of these drugs may come with their own side effects, they are generally safer than Cylert. When consulting a doctor about your child’s ADHD, you should have a frank discussion about any possible side effects that the medicine may have on your child.
 

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